Evaluating the Effect of Itraconazole on Pathologic Complete Response Rates in Esophageal Cancer

PHASE2RecruitingINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

June 24, 2019

Primary Completion Date

June 24, 2026

Study Completion Date

September 29, 2026

Conditions

Esophagus AdenocarcinomaEsophagus Squamous Cell CarcinomaGastroesophageal Junction Adenocarcinoma

Interventions

DRUG

Itraconazole

Oral administration of itraconazole twice daily from completion of neoadjuvant chemoradiation until esophagectomy.

Trial Locations (1)

RECRUITING

Dallas VA Medical Center, Dallas