Automated Insulin Delivery in Elderly With Type 1 Diabetes (AIDE T1D)

PHASE4CompletedINTERVENTIONAL
Enrollment

82

Participants

Timeline

Start Date

September 28, 2020

Primary Completion Date

September 14, 2023

Study Completion Date

January 5, 2024

Conditions
Type 1 Diabetes Mellitus
Interventions
DEVICE

Tandem t:slim X2 with HCL or PLGS

"The system components include the t:slim X2 with Control-IQ Technology and the Dexcom CGM G6. The modular control algorithm has a safety supervision module that limits insulin delivery to prevent hypoglycemia at all times. The algorithm gradually decreases hyperglycemia from bedtime to reach a target of 120 mg/dL by waking time. During awake hours, the control algorithm attempts to maintain glucose within a target range (112.5 to 160 mg/dL) with meal time insulin boluses delivered based on usual bolus procedures undertaken by patients on an insulin pump (Hybrid closed loop).~The system components include the t:slim X2 with with Basal-IQ Technology and the Dexcom CGM G6. The PLGS System is able to stop and resume basal insulin delivery automatically in response to predicted or low sensor glucose values, thereby reducing the incidence and duration of hypoglycemic episodes. The pump includes the hypoglycemia minimization strategy that will issue insulin delivery commands."

Trial Locations (4)

13214

SUNY Upstate, Syracuse

19104

University of Pennsylvania, Philadelphia

32803

AdventHealth Diabetes Institute, Orlando

55905

Mayo Clinic, Rochester

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

collaborator

DexCom, Inc.

INDUSTRY

collaborator

Tandem Diabetes Care, Inc.

INDUSTRY

collaborator

University of Minnesota - Advanced Research and Diagnostic Laboratory

UNKNOWN

collaborator

Mayo Clinic

OTHER

collaborator

University of Pennsylvania

OTHER

collaborator

AdventHealth Diabetes Institute

UNKNOWN

collaborator

Washington State University

OTHER

lead

Jaeb Center for Health Research

OTHER