Hypotaurine Supplementation Benefits in Cryopreservation

CompletedOBSERVATIONAL
Enrollment

33

Participants

Timeline

Start Date

May 1, 2014

Primary Completion Date

August 1, 2018

Study Completion Date

May 1, 2019

Conditions
CryopreservationHuman Spermatozoa ParametersHypotaurine SupplementationSpermatozoa DNA Alterations
Interventions
OTHER

Hypotaurine : antioxidant and osmoregulator

"Hypotaurine has protective effects on sperm motility, capacitation and acrosome reaction and reduces apoptotic markers.~Hypotaurine (50mM) was added in density gradient centrifugation, washing and cryopreservation media washing and cryopreservation media before spermatozoa freezing"

All Listed Sponsors
collaborator

Université d'Auvergne, Institut National de la Santéet de la Recherche Médicale

UNKNOWN

collaborator

Université d'Auvergne, Centre National de la Recherche Scientifique

UNKNOWN

collaborator

University Hospital, Clermont-Ferrand, Hematology laboratory

UNKNOWN

lead

University Hospital, Clermont-Ferrand

OTHER

NCT04011813 - Hypotaurine Supplementation Benefits in Cryopreservation | Biotech Hunter | Biotech Hunter