Portico Next Generation Approval Study

NAActive, not recruitingINTERVENTIONAL
Enrollment

333

Participants

Timeline

Start Date

September 17, 2019

Primary Completion Date

January 12, 2023

Study Completion Date

December 31, 2027

Conditions
Symptomatic Severe Aortic Stenosis
Interventions
DEVICE

Portico™ NG (Navitor) Valve and FlexNav™ Delivery System

Subjects will undergo transcatheter aortic valve implantation (TAVI) with the new generation Portico NG (Navitor) valve and second-generation FlexNav Delivery system via a transfemoral or alternative access approach according to the site's anesthesia protocol for TAVR procedures.

DEVICE

Navitor Titan Valve (35mm) Valve and Large FlexNav™ Delivery System

Subjects will undergo transcatheter aortic valve implantation (TAVI) with the Navitor Titan valve and large FlexNav Delivery system via a transfemoral or alternative access approach according to the site's anesthesia protocol for TAVR procedures.

Trial Locations (28)

2100

Rigshospitalet, Copenhagen

3004

The Alfred Hospital, Melbourne

5000

St. Andrew's Hospital, Adelaide

6150

Fiona Stanley Hospital, Murdoch

10032

Columbia University Medical Center/NYPH, New York

10467

Montefiore Medical Center - Moses Division, New York

12208

Albany Medical Center, Albany

15232

University of Pittsburgh Medical Center, Pittsburgh

20010

Washington Hospital Center, Washington D.C.

20097

Policlinico San Donato, San Donato Milanese

23507

Sentara Norfolk General Hospital, Norfolk

28801

Mission Health & Hospitals, Asheville

38120

Baptist Memorial Hospital, Memphis

44106

University Hospitals Cleveland Medical Center, Cleveland

46240

St. Vincent Hospital, Indianapolis

48912

Sparrow Clinical Research Institute, Lansing

55407

Minneapolis Heart Institute, Minneapolis

60453

Advocate Christ Medical Center, Oak Lawn

67214

Via Christi Regional Medical Center, Wichita

75093

The Heart Hospital Baylor Plano, Plano

77030

The Methodist Hospital, Houston

84790

Intermountain St. George Regional Hospital, St. George

90048

Cedars-Sinai Medical Center, Los Angeles

91360

Los Robles Regional Medical Center, Thousand Oaks

97225

Providence St. Vincent Medical Center, Portland

07962

Atlantic Health System - Morristown Memorial Hospital, Morristown

BT12 6BA

Royal Victoria Hospital, Belfast

SA6 6NL

Morriston Hospital - ABM University Health Board, Morriston

Sponsors
All Listed Sponsors
lead

Abbott Medical Devices

INDUSTRY