Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major: A Multicenter, Prospective Clinical Study

PHASE4CompletedINTERVENTIONAL
Enrollment

823

Participants

Timeline

Start Date

July 5, 2019

Primary Completion Date

July 31, 2023

Study Completion Date

October 31, 2023

Conditions
Thalassemia Major
Interventions
DRUG

Busulfan

Busulfan(4 mg/kg/day,4 days)

DRUG

Cyclophosphamide

Cyclophosphamide(50 mg/kg/day,4 days)

DRUG

Fludarabine

Fludarabine(50 mg/m2/day,3 days)

DRUG

Thymoglobulin

Thymoglobulin(2.5 mg/kg/day,4 days)

DRUG

cyclosporine A

cyclosporine A

DRUG

Mycophenolate mofetil

Mycophenolate mofetil(0.25g/day)

DRUG

Tacrolimus

Tacrolimus

DRUG

Methotrexate

Methotrexate

Trial Locations (1)

510515

First Affiliated Hospital of Guangxi Medical University, Nanning

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Peking University People's Hospital

OTHER

collaborator

Ruijin Hospital

OTHER

collaborator

The 923rd Hospital of Joint Logistics Support Force of People's Liberation Army

OTHER

collaborator

LiuZhou People's Hospital

OTHER

collaborator

The First People's Hospital of Yunnan

OTHER

collaborator

Liuzhou Workers' Hospital

OTHER_GOV

collaborator

Xinqiao Hospital of Chongqing

OTHER

collaborator

Affiliated Hospital of Youjiang University of Ethnic Medicine

UNKNOWN

collaborator

Hainan People's Hospital

OTHER

collaborator

Maoming People's Hospital

OTHER

collaborator

Red Cross Hospital of Yulin City

OTHER

collaborator

Guilin Medical College

OTHER

collaborator

Wuzhou People's Hospital

UNKNOWN

collaborator

Guangxi Autonomous Region People's Hospital

UNKNOWN

collaborator

The 920th Hospital of Joint Logistics Support Force of People's Liberation Army

UNKNOWN

lead

First Affiliated Hospital of Guangxi Medical University

OTHER