Cascade Testing in Families With Newly Diagnosed Hereditary Breast and Ovarian Cancer Syndrome

Active, not recruitingOBSERVATIONAL
Enrollment

118

Participants

Timeline

Start Date

March 1, 2019

Primary Completion Date

June 11, 2025

Study Completion Date

April 23, 2027

Conditions
BRCA-Mutated Ovarian CarcinomaBRIP1 Gene MutationMSH2 A636PMLH1 Gene MutationMSH6 Gene MutationPMS2 Gene MutationEPCAMRAD51C Gene Mutation
Interventions
OTHER

CASCADE genetic screening

Family-based cohort of mutation carriers, blood relatives who test negative, and untested blood relatives

Trial Locations (1)

10016

NYU Langone Health, New York

All Listed Sponsors
lead

NYU Langone Health

OTHER

NCT04009148 - Cascade Testing in Families With Newly Diagnosed Hereditary Breast and Ovarian Cancer Syndrome | Biotech Hunter | Biotech Hunter