A Study of Low-dose Intracoronary Thrombolytic Therapy in STEMI (Heart Attack) Patients.

PHASE3RecruitingINTERVENTIONAL
Enrollment

445

Participants

Timeline

Start Date

October 14, 2021

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2026

Conditions
STEMIElevated IMR (>32)
Interventions
DRUG

Tenecteplase (1/3 systemic weight based dose)

50mg reconstituted to 20mL for intracoronary infusion at 1/3 weight based dose.

OTHER

Sterile water for injection (WFI)

Placebo comparative arm.

Trial Locations (22)

1023

NOT_YET_RECRUITING

Auckland City Hospital, Auckland

2031

NOT_YET_RECRUITING

Prince of Wales Hospital, Randwick

2050

RECRUITING

Royal Prince Alfred Hospital, Camperdown

2086

NOT_YET_RECRUITING

Northern Beaches Hospital, Frenchs Forest

2139

RECRUITING

Concord Repatriation General Hospital, Concord

2170

RECRUITING

Liverpool Hospital, Liverpool

2200

NOT_YET_RECRUITING

Bankstown-Lidcombe Hospital, Bankstown

2305

RECRUITING

John Hunter Hospital, New Lambton Heights

2500

WITHDRAWN

Wollongong Hospital, Wollongong

2820

NOT_YET_RECRUITING

Wellington Hospital, Wellington

3021

RECRUITING

Sunshine Hospital, Saint Albans

3076

RECRUITING

The Northern Hospital, Epping

3128

RECRUITING

Box Hill Hospital, Box Hill

3168

RECRUITING

Jessie McPherson Private Hospital, Clayton

RECRUITING

Victorian Heart Hospital, Clayton

3199

RECRUITING

Frankston Hospital, Frankston

3240

RECRUITING

Waikato Hospital, Hamilton

4710

NOT_YET_RECRUITING

Christchurch Hospital, Christchurch

5000

RECRUITING

Royal Adelaide Hospital, Adelaide

5112

RECRUITING

Lyell McEwin Hospital, Elizabeth Vale

6000

RECRUITING

Royal Perth Hospital, Perth

6150

NOT_YET_RECRUITING

Fiona Stanley Hospital, Murdoch

All Listed Sponsors
lead

University of Sydney

OTHER