NCT03997383 - APOLLO-B: A Study to Evaluate Patisiran in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR Amyloidosis With Cardiomyopathy) | Biotech Hunter

Enrollment

360

Participants

Timeline

Start Date

September 4, 2019

Primary Completion Date

June 20, 2022

Study Completion Date

March 1, 2027

Conditions

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

Interventions

DRUG

Placebo

Normal saline (0.9% NaCl) matching volume of patisiran doses will be administered intravenously.

DRUG

Patisiran

Patisiran will be administered by intravenous (IV) infusion.

Trial Locations (67)

10029

Clinical Trial Site, New York

10034

Clinical Trial Site, New York

19140

Clinical Trial Site, Philadelphia

21287

Clinical Trial Site, Baltimore

37232

Clinical Trial Site, Nashville

44195

Clinical Trial Site, Cleveland

55905

Clinical Trial Site, Rochester

60201

Clinical Trial Site, Evanston

60637

Clinical Trial Site, Chicago

63110

Clinical Trial Site, St Louis

66103

Clinical Trial Site, Kansas City

75246

Clinical Trial Site, Dallas

90048

Clinical Trial Site, Los Angeles

02118

Clinical Trial Site, Boston

Unknown

Clinical Trial Site, Córdoba

Clinical Trial Site, Box Hill

Clinical Trial Site, Westmead

Clinical Trial Site, Aalst

Clinical Trial Site, Hasselt

Clinical Trial Site, Liège

Clinical Trial Site, Roeselare

Clinical Trial Site, Porto Alegre

Clinical Trial Site, Ribeirão Preto

Clinical Trial Site, Rio de Janeiro

Clinical Trial Site, São Paulo

Clinical Trial Site, Sofia

Clinical Trial Site, Santiago

Clinical Trial Site, Brno

Clinical Trial Site, Prague

Clinical Trial Site, Aarhus

Clinical Trial Site, Copenhagen

Clinical Trial Site, Odense

Clinical Trial Site, Créteil

Clinical Trial Site, Rennes

Clinical Trial Site, Toulouse

Clinical Trial Site, Lai Chi Kok

Clinical Trial Site, Bologna

Clinical Trial Site, Florence

Clinical Trial Site, Messina

Clinical Trial Site, Pavia

Clinical Trial Site, Fukuoka

Clinical Trial Site, Kumamoto

Clinical Trial Site, Kurume

Clinical Trial Site, Matsumoto

Clinical Trial Site, Nagoya

Clinical Trial Site, Osaka

Clinical Trial Site, Tokyo

Clinical Trial Site, Mexico City

Clinical Trial Site, Groningen

Clinical Trial Site, Maastricht

Clinical Trial Site, Christchurch

Clinical Trial Site, Hamilton

Clinical Trial Site, Viseu

Clinical Trial Site, Seoul

Clinical Trial Site, Stockholm

Clinical Trial Site, Taipei

Clinical Trial Site, Birmingham

Clinical Trial Site, Cardiff

Clinical Trial Site, Glasgow

Clinical Trial Site, London

Clinical Trial Site, Manchester

Clinical Trial Site, Stockton-on-Tees

S2000DSR

Clinical Trial Site, Rosario

S2000DTC

Clinical Trial Site, Rosario

S2000PBJ

Clinical Trial Site, Rosario

05403-000

Clinical Trial Site, São Paulo

14048-900

Clinical Trial Site, São Paulo