Neuro/Sacituzumab Govitecan/Breast Brain Metastasis/Glioblastoma/Ph 0

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

July 17, 2019

Primary Completion Date

June 3, 2022

Study Completion Date

March 20, 2024

Conditions
Glioblastoma
Interventions
DRUG

Sacituzumab Govitecan

All 20 subjects will receive study drug Sacituzumab Govitecan preoperatively. Intraoperative tissue collection will follow with contemporaneous CSF (depending on tumor location) and whole blood (serum) sampling. Samples will be tested for total SN-38and free SN-38, as well as SN-38G. Following recovery from surgery, patients will resume treatment

Trial Locations (1)

78229

Mays Cancer Center, UT Health San Antonio, San Antonio

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Gilead Sciences

INDUSTRY

lead

The University of Texas Health Science Center at San Antonio

OTHER

NCT03995706 - Neuro/Sacituzumab Govitecan/Breast Brain Metastasis/Glioblastoma/Ph 0 | Biotech Hunter | Biotech Hunter