NCT03994211 - Study to Investigate the Effect of Rifampin and Itraconazole on the Action of Pamiparib in Participants With Cancer | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

May 29, 2019

Primary Completion Date

October 25, 2019

Study Completion Date

August 6, 2021

Conditions

Solid Tumor

Interventions

DRUG

pamiparib 60 mg

Single dose of 60 mg pamiparib orally on Days 1 and 10

DRUG

pamiparib 20 mg

Single dose of 20 mg pamiparib orally on days 1 and 7

DRUG

itraconazole

200 mg itraconazole once a day al Day 3 to day 8

DRUG

rifampin

600 mg rifampin once a day from days 3 to 11

DRUG

pamiparib

60 mg pamiparib orally twice a day in 28-day cycles

Trial Locations (4)

Republican Clinical Hospital, Oncology Department, Chiinu

Summit Clinical Research, Sro, Bratislava

Arensia Exploratory Medicine Llc, Tbilisi

Szpital Luxmed, Warsaw