Phase II Study to Evaluate Modified Folfirinox and Stereotactic Body Radiation Therapy in Non-metastatic Unresectable Pancreatic Adenocarcinoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

September 19, 2019

Primary Completion Date

August 31, 2026

Study Completion Date

February 28, 2027

Conditions
Pancreatic Cancer
Interventions
DRUG

mFOLFIRINOX

Patients will receive 6-12 cycles of mFOLFIRINOX every 2 weeks

RADIATION

Stereotactic body radiotherapy (SBRT)

Stereotactic body radiotherapy (SBRT) will be delivered to the primary tumor and any adjacent involved lymph nodes to 33 Gy in 5 fractions over the course of 2 weeks, and within 4 weeks of chemotherapy.

Trial Locations (1)

06511

RECRUITING

Yale University School of Medicine, New Haven

All Listed Sponsors
lead

Yale University

OTHER