Treatment of HOsPitalised Inpatients for Hepatitis C (TOPIC): Therapeutic Intervention Enhancing Care Linkage in People Who Inject Drugs

NARecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

February 12, 2021

Primary Completion Date

February 12, 2025

Study Completion Date

February 12, 2025

Conditions
Hepatitis CLiver InflammationLiver Cirrhoses
Interventions
DRUG

Glecaprevir/Pibrentasvir 100 MG-40 MG Oral Tablet

8 weeks of 3 x co-formulated tablets of glecaprevir (100mg) and pibrentasvir (40mg) once daily or 4 weeks of 1 tablet sofosbuvir 400 mg and a three fixed-dose combination of glecaprevir/pibrentasvir 100/40 mg tablets administered once daily

DRUG

Sofosbuvir 400 MG + Glecaprevir/Pibrentasvir 100 MG-40 MG Oral Tablet

4 weeks of 1 x sofosbuvir (400mg) tablet and 3 x co-formulated tablets of glecaprevir (100mg) and pibrentasvir (40mg) once daily

Trial Locations (7)

2010

RECRUITING

St Vincent's Hospital Sydney, Sydney

2031

NOT_YET_RECRUITING

Prince of Wales Hospital, Randwick

2145

NOT_YET_RECRUITING

Westmead Hospital, Westmead

2148

NOT_YET_RECRUITING

Blacktown Mt Druitt Hospital, Sydney

3004

NOT_YET_RECRUITING

The Alfred Hospital, Melbourne

3065

NOT_YET_RECRUITING

St Vincent's Hospital, Melbourne

5000

NOT_YET_RECRUITING

Royal Adelaide Hospital, Adelaide

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Kirby Institute

OTHER_GOV