40
Participants
Start Date
August 22, 2019
Primary Completion Date
March 15, 2023
Study Completion Date
June 15, 2026
Avelumab addition to perioperative chemotherapy in GC and GEJC
Avelumab addition to perioperative chemotherapy in GC and GEJC. Peri-operatory treatment consisting of four cycles (each cycle is 14 days) of neoadjuvant chemotherapy (docetaxel, oxaliplatin and fluorouracil/leucovorin) plus avelumab previous to surgery. Surgery is recommended to be scheduled 4 to 6 weeks after the last dose. Afterwards (4 to 10 weeks after surgery), four cycles of adjuvant therapy with the same schema, followed by avelumab up to one year. There will be be a follow-up of 5 years.
Vall d'Hebron Institute of Oncology, Barcelona
Vall d'Hebron Institute of Oncology
OTHER