Atezolizumab and Tiragolumab in Patients With NSCLC or Advanced Solid Tumors Having Had Prior Treatment With a PD-1 Inhibitor

PHASE2CompletedINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

August 30, 2019

Primary Completion Date

August 9, 2024

Study Completion Date

August 9, 2024

Conditions
Non-Small Cell Lung CancerSolid Tumor
Interventions
DRUG

Atezolizumab

Atezolizumab at a flat dose of 1200 mg IV every 3 weeks

DRUG

Standard of Care Chemotherapy

Platinum-based standard of care doublet chemotherapy (or triplet if bevacizumab is used) will be given by IV every 3 weeks. Platinum chemotherapy may be cisplatin or carboplatin chosen based on histology and at the discretion of the treating investigator. It should be administered according to the directions in the approved labeling.

DRUG

Tiragolumab

Tiragolumab at a flat dose of 600 mg IV every 3 weeks

Trial Locations (7)

32308

Florida Cancer Specialists - Panhandle, Tallahassee

33401

Florida Cancer Specialists - East, West Palm Beach

33705

Florida Cancer Specialists - North, St. Petersburg

33991

Florida Cancer Specialists - South, Fort Myers

37203

Tennessee Oncology, PLLC, Nashville

37404

Tennessee Oncology - Chattanooga, Chattanooga

64132

MidAmerica Division, Inc., c/o Research Medical Center (HCA Midwest), Kansas City

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

lead

SCRI Development Innovations, LLC

OTHER