A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

345

Participants

Timeline

Start Date

August 12, 2019

Primary Completion Date

November 15, 2027

Study Completion Date

November 15, 2027

Conditions
Metastatic Castration-Resistant Prostate Cancer (mCRPC)Clear Cell Renal Cell Carcinoma (ccRCC)
Interventions
DRUG

REGN5678

Administered as per the protocol

DRUG

Cemiplimab

Administered as per the protocol

Trial Locations (17)

10029

RECRUITING

Icahn School of Medicine at Mount Sinai, New York

10032

RECRUITING

Columbia University - The Trustees of Columbia University in the City of New York, New York

10461

RECRUITING

Montefiore Medical Center, New York

19107

RECRUITING

Thomas Jefferson University Hospital, Philadelphia

22908

RECRUITING

Emily Couric Clinical Cancer Center, Charlottesville

33612

RECRUITING

Moffitt Cancer Center - McKinley Drive, Tampa

77030

RECRUITING

MD Anderson Cancer Center, Houston

80218

RECRUITING

Sarah Cannon Research Institute (SCRI), Denver

85234

RECRUITING

Banner MD Anderson Cancer Center, Gilbert

85724

RECRUITING

University of Arizona, Tucson

90404

RECRUITING

John Wayne Cancer Institute (JWCI), Santa Monica

97213

WITHDRAWN

Providence Portland Medical Center, Portland

97239

RECRUITING

Oregon Health & Science University (3485 S. Bond), Portland

06520

RECRUITING

Yale University Hospital, New Haven

02114

RECRUITING

Massachusetts General Hospital, Boston

10016-4744

RECRUITING

NYU Langone Health Perlmutter Cancer Center, New York

02903

RECRUITING

Lifespan Cancer Institute, Providence

All Listed Sponsors
lead

Regeneron Pharmaceuticals

INDUSTRY