NCT03972072View on ClinicalTrials.gov

MRI - Guided Adaptive RadioTHerapy for Reducing XerostomiA in Head and Neck Cancer (MARTHA-trial)

NAActive, not recruitingINTERVENTIONAL
Enrollment

49

Participants

Timeline

Start Date

October 15, 2019

Primary Completion Date

May 21, 2025

Study Completion Date

May 21, 2026

Conditions
Head and Neck CancerXerostomia Due to Radiotherapy
Interventions
OTHER

Pre-defined MR-linac based IGRT and plan adaptation protocol

daily MR-imaging/MR guided radiotherapy once weekly offline plan adaptation to a total of 6

DIAGNOSTIC_TEST

salivary flow measurements

baseline, 6 month-, 12 month- and 24 month-follow up salivary flow measurements and LENT-SOMA subjective/objective evaluation of xerostomia

Trial Locations (1)

8091

Zurich University Hospital, Zurich

All Listed Sponsors
lead

Panagiotis Balermpas

OTHER