47
Participants
Start Date
October 28, 2019
Primary Completion Date
May 27, 2025
Study Completion Date
May 27, 2025
Cladribine
All participants will receive cladribine 10 mg tablets at a cumulative dosage of 3.5 mg/kg divided into 2 treatment courses as per the United States Prescribing Information (USPI) (1.75 mg/kg per treatment course; Year 1 and Year 2 treatment). Patients will be randomized 1:2:2:1 to receive a total of 2 Lumbar Punctures at specific time points during the treatment cycle.
University of Pennsylvania, Philadelphia
Medical College of Wisconsin, Milwaukee
Washington University School of Medicine, St Louis
Oklahoma Medical Research Foundation, Oklahoma City
University of Texas Southwestern Medical Center, Dallas
Collaborators (1)
EMD Serono
INDUSTRY
Washington University School of Medicine
OTHER