Standard Versus Super-extended Lymphadenectomy After Neo-adjuvant Chemotherapy for Gastric Cancer

PHASE3RecruitingINTERVENTIONAL
Enrollment

539

Participants

Timeline

Start Date

November 5, 2018

Primary Completion Date

November 1, 2023

Study Completion Date

November 1, 2028

Conditions
Locally Advanced Gastric Cancer
Interventions
PROCEDURE

Gastrectomy with D2 lymphadenectomy

Patients who are assigned to the neoadjuvant chemotherapy+ surgical D2 treatment group will undergo either subtotal or total gastrectomy, depending on the location of the primary tumour. Standardized D2-lymph node dissection is required with specific information about lymph node stations.

PROCEDURE

Gastrectomy with D2plus lymphadenectomy

Patients who are assigned to the neoadjuvant chemotherapy + surgical D2+ extended lymphadenectomy treatment group will undergo either subtotal or total gastrectomy, depending on the location of the primary tumour. Standardized D2+ lymph node dissection plus resection of stations 8p, 12p, 13, 14v, 16a2/b1 is required with specific information about lymph node stations.

Trial Locations (1)

53100

RECRUITING

General and Surgical Oncology Department, University of Siena, Siena

All Listed Sponsors
lead

University of Siena

OTHER

NCT03961373 - Standard Versus Super-extended Lymphadenectomy After Neo-adjuvant Chemotherapy for Gastric Cancer | Biotech Hunter | Biotech Hunter