Response of Bony Metastasis to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancers With Actionable Driver Mutations.

RecruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

April 28, 2020

Primary Completion Date

March 5, 2028

Study Completion Date

April 28, 2028

Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
BIOLOGICAL

Tyrosine Kinase Inhibitor

Targeted therapy given as standard of care.

DRUG

Zoledronic Acid 4 MG/100 ML Intravenous Solution [ZOMETA]

Given Q4 weeks as standard of care

DRUG

Denosumab 120 MG/1.7 ML Subcutaneous Solution [XGEVA]

Given Q12 weeks for bone disease as standard of care

Trial Locations (2)

80045

RECRUITING

University of Colorado Hospital, Aurora

80124

RECRUITING

Lone Tree Medical Center, Lone Tree

All Listed Sponsors
collaborator

Cancer League of Colorado

OTHER

lead

University of Colorado, Denver

OTHER