Venetoclax and Selinexor in Treating Patients with Relapsed or Refractory High Risk Hematologic Malignancies

PHASE1CompletedINTERVENTIONAL
Enrollment

78

Participants

Timeline

Start Date

June 21, 2019

Primary Completion Date

September 1, 2024

Study Completion Date

September 1, 2024

Conditions
Diffuse Large B-cell LymphomaAcute Myeloid LeukemiaNon-Hodgkin's Lymphoma
Interventions
DRUG

Venetoclax

Given by mouth

DRUG

Selinexor

Given by mouth

Trial Locations (4)

14263

Roswell Park Cancer Center, Buffalo

37232

Vanderbilt-Ingram Cancer Center, Nashville

44106

University Hospitals of Cleveland, Cleveland

75390-8565

University of Texas Southwestern Medical Center, Dallas

Sponsors
All Listed Sponsors
collaborator

Karyopharm Therapeutics Inc

INDUSTRY

collaborator

AbbVie

INDUSTRY

lead

Sanjay Mohan

OTHER