Efficiency of Everolimus for the Treatment of Kidney Transplanted Patients Presenting a Missing Self-induced NK-mediated Rejection

NARecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

December 3, 2020

Primary Completion Date

December 3, 2027

Study Completion Date

December 3, 2027

Conditions
Kidney Transplant Failure and Rejection
Interventions
DRUG

Everolimus

Patients will received everolimus (CERTICAN), oral form, at the necessary dose to obtain trough levels between 6 and 8 ng/ml, during 6 months. Everolimus will replace the anti-proliferative drug they have before (azathioprine or mycophenolic acid). Everolimus will be associated with corticosteroids (prednisolone) and a calcineurin inhibitor (tacrolimus or cyclosporin).

Trial Locations (1)

69003

RECRUITING

Service de transplantation, néphrologie et immunologie clinique, Hôpital Edouard Herriot (HCL), Lyon

All Listed Sponsors
lead

Hospices Civils de Lyon

OTHER