Safety and Tolerability of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy (IgAN)

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

103

Participants

Timeline

Start Date

April 8, 2019

Primary Completion Date

October 1, 2025

Study Completion Date

April 13, 2026

Conditions
IgA Nephropathy
Interventions
DRUG

BION-1301 Single Dose

A solution for IV infusion administered as a single dose.

DRUG

Placebo Single Dose

A solution by IV infusion administered as a single dose.

DRUG

BION-1301 Multiple Doses

A solution for IV infusion or SC injections (Part 3 only) administered as multiple doses.

DRUG

Placebo Multiple Doses

A solution by IV infusion administered as multiple doses.

DRUG

BION-1301 Single Dose

SC injection administration as a single dose using vials or pre-filled syringes (PFS) (Part 4 only).

Trial Locations (16)

10444

National Health Insurance Service Ilsan Hospital, Goyang-si

11923

Hanyang University Guri Hostpital, Guri-si

12065

New York Nephrology, Clifton Park

13620

Seoul National University Bundang Hospital, Seongnam-si

14068

Hallym University Sacred Heart Hospital, Anyang-si

31151

Soon Chun Hyang University Hospital Cheonan, Cheonan

32806

Nephrology Associates of Central Florida, Orlando

33618

Elixia Tampa, LLC, Tampa

73116

Chris Sholer, P.C., Oklahoma City

75230

Liberty Research Center, Dallas

76012

Liberty Research Center, Arlington

77054

Prolato Clinical Research Center, Houston

80230

Colorado Kidney Care, P.C., Denver

91324

Amicis Research Center, Northridge

L7 8XP

Liverpool University Hospital NHS Foundation Trust, Liverpool

HA1 3UJ

PAREXEL Early Phase Clinical Unit, London

Sponsors
All Listed Sponsors
lead

Novartis Pharmaceuticals

INDUSTRY