Endoscopic Variceal Ligation in Children

CompletedOBSERVATIONAL
Enrollment

60

Participants

Timeline

Start Date

January 1, 2014

Primary Completion Date

April 30, 2019

Study Completion Date

April 30, 2019

Conditions
Esophageal Varices in Cirrhosis of the LiverUpper Gastrointestinal BleedingEndoscopyChild
Interventions
PROCEDURE

Endoscopic Variceal Ligation

Endoscopic varices ligation was performed with a six-shooter multiband ligator (Cook Medical, Limerick, Ireland) if medium to large varices or reddish spots, regardless of the grade of the varix, were observed. Each varix was ligated 1-2 cm above the gastro-esophageal junction, with 1 or 2 rubber bands and using no more than 5 rubber bands per session.

DRUG

Non-Selective Beta-Blocking Agent

Patients of the Propranolol group that presented medium to large esophageal varices without contraindication to Non-Selective Beta-Blockers, received propranolol, 1 mg/Kg/day every 8 hours, titrated to reduce the basal heart rate in 25% and not exceeding 5 mg/Kg/day. Patients were evaluated monthly until this reduction in heart rate was achieved, and every three to six months thereafter.

All Listed Sponsors
lead

Hospital Vall d'Hebron

OTHER

NCT03943784 - Endoscopic Variceal Ligation in Children | Biotech Hunter | Biotech Hunter