A Study to Investigate Sitravatinib as Monotherapy and in Combination With Tislelizumab in Participants With Unresectable Locally Advanced or Metastatic Hepatocellular Carcinoma or Gastric/Gastroesophageal Junction Cancer

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

111

Participants

Timeline

Start Date

February 28, 2019

Primary Completion Date

March 31, 2023

Study Completion Date

March 31, 2023

Conditions
Carcinoma, HepatocellularGastric/Gastroesophageal Junction Cancer
Interventions
DRUG

Sitravatinib

Administered orally as a capsule

DRUG

Tislelizumab

Administered intravenously

Trial Locations (18)

100142

Beijing Cancer Hospital, Beijing

110042

Liaoning Cancer Hospital and Institute, Shenyang

150000

Harbin Medical University Cancer Hospital, Harbin

200000

Fudan University Shanghai Cancer Center, Shanghai

200032

Affiliated Zhongshan Hospital of Fudan University, Shanghai

200123

Shanghai East Hospital Branch Hospital, Shanghai

210002

General Hospital of Eastern Theatre Command Qihuaiyuan Branch(the St Hospital of Chinese Pla), Nanjing

230601

The Second Hospital of Anhui Medical University, Hefei

310003

The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou

310016

Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou

310022

Zhejiang Cancer Hospital, Hangzhou

330006

The First Affiliated Hospital of Nanchang University Branch Donghu, Nanchang

350001

Fujian Medical University Union Hospital, Fuzhou

430022

Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan

430071

Zhongnan Hospital of Wuhan University Wuhan, Wuhan

430079

Hubei Cancer Hospital, Wuhan

510000

Sun Yat Sen Memorial Hospital, Sun Yat Sen University (North), Guangzhou

510515

Nanfang Hospital of Southern Medical University, Guangzhou

Sponsors

Lead Sponsor

All Listed Sponsors
lead

BeiGene

INDUSTRY