Intravenous Autologous CD19 CAR-T Cells for R/R B-ALL

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

March 19, 2019

Primary Completion Date

January 18, 2027

Study Completion Date

March 18, 2027

Conditions
Relapsed B Acute Lymphoblastic LeukaemiaRefractory B Acute Lymphoblastic Leukaemia
Interventions
BIOLOGICAL

CD19 CAR-T CELLS

CD19 CAR-T cells will be administered after completion of the lymphodepletion chemotherapy.

DRUG

Cyclophosphamide

Patients will receive lymphodepleting chemotherapy consisting of Cyclophosphamide 250 - 300 mg/m2/day IV(Day -5, Day -4, Day -3 ).

DRUG

Fludarabine

Patients will receive lymphodepleting chemotherapy consisting of Fludarabine 25-30 mg/m2/day IV (Day -5, Day -4, Day -3 ).

Trial Locations (1)

56000

RECRUITING

UKM Medical Centre, Bandar Tun Razak

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Gaia Science

OTHER

lead

National University of Malaysia

OTHER

NCT03937544 - Intravenous Autologous CD19 CAR-T Cells for R/R B-ALL | Biotech Hunter | Biotech Hunter