Study to Evaluate Safety Tolerability & Efficacy of Kyprolis (Carfilzomib) in Relapsed or Refractory Multiple Myeloma

PHASE4CompletedINTERVENTIONAL
Enrollment

101

Participants

Timeline

Start Date

September 16, 2019

Primary Completion Date

March 23, 2023

Study Completion Date

June 27, 2025

Conditions
Relapsed Refractory Multiple Myeloma
Interventions
DRUG

Drug: Carfilzomib + Dexamethasone

"Drug: Carfilzomib + Dexamethasone~* Carfilzomib will be administered as a 30-minute infusion.~* Dexamethasone will be taken by mouth or intravenously."

DRUG

Drug: Carfilzomib + Lenalidomide + Dexamethasone

"Drug: Carfilzomib + Lenalidomide + Dexamethasone~* Carfilzomib will be administered as a 10 minute infusion.~* Lenalidomide will be taken orally.~* Dexamethasone will be taken by mouth or intravenously."

Trial Locations (17)

250001

Valentis Cancer Hospital, Meerut

411004

Deenanath Mangeshkar Hospital and Research Centre, Pune

500033

Apollo Hospital, Hyderabad

560054

M S Ramaiah Memorial Hospital, Bangalore

560064

Cytecare Cancer Hospitals, Bengaluru

590010

K L E S Dr Prabhakar Kore Hospital and Medical Research Centre, Belagavi

600020

Cancer Institute WIA, Chennai

637001

Thangam Cancer Centre, Namakkal

673008

Government Medical College, Kozhikode

682027

Aster Medcity, Kochi

500 082

Yashoda Hospital, Hyderabad

400 012

Tata Memorial Hospital, Mumbai

400 056

Mumbai Oncocare Center, Mumbai

422 002

Navsanjeevani Hospital, Nashik

422 004

Heath Care Group Manavata Cancer Centre, Nashik

605 006

Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry

700 094

Netaji Subhash Chandra Bose Cancer Research Institute, Kolkata

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Amgen

INDUSTRY