NCT03934372 - Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

January 29, 2020

Primary Completion Date

January 30, 2026

Study Completion Date

January 30, 2026

Conditions

Acute Myeloid LeukemiaAccelerated Phase Chronic Myeloid LeukemiaBlast Phase Chronic Myeloid LeukemiaChronic Phase Chronic Myeloid LeukemiaAcute Lymphoblastic LeukemiaAcute Lymphocytic LeukemiaLeukemiaLymphomaSolid Tumors

Interventions

DRUG

Ponatinib

Ponatinib administered as a tablet or age-appropriate formulation for pediatric participants according to age-based cohort assignment.

Trial Locations (32)

10126

RECRUITING

A.O.U Citta Della Salute E Della Scienza Di Torino Presidio Ospedaliero Infantile Regina Margherita, Torino

14141

RECRUITING

Karolinska University Hospital Solna, Stockholm

16147

RECRUITING

Ospedale Pediatrico G. Gaslini, Genova

20133

RECRUITING

Comitato Etico Fondazione Irccs Istituto Nazionale Dei Tumori Milano, Milan

20900

NOT_YET_RECRUITING

Ospedale San Gerardo - Asst Monza, Monza

RECRUITING

University of Milano Bicocca, Monza

25123

RECRUITING

Asst Degli Spedali Civili Di Brescia, Brescia

27100

RECRUITING

Comitato Di Bioetica Della Fondazione Irccs Policlinico San Matteo, Pavia

28009

RECRUITING

Hospital Infantil Unversitario Nino Jesus, Madrid

28046

COMPLETED

Hospital Universitario de La Paz, Madrid

35700

RECRUITING

Chu de Rennes - Hospital Sud, Rennes

40138

RECRUITING

Aou Policlinico S. Orsola-Malpighi, Bologna

45147

NOT_YET_RECRUITING

Universitatsklinikum Essen, Essen

46026

RECRUITING

Hospital Universitari I Politecnic La Fe, Valencia

75019

RECRUITING

Hopital Robert Debre, Paris

75571

RECRUITING

Armand Trousseau Hospital, Paris

80122

NOT_YET_RECRUITING

Aorn Santobono Pausilipon, Naples

86021

RECRUITING

Centre Hospitalier Universitaire de Poitiers, Poitiers

91054

NOT_YET_RECRUITING

Universitaetsklinikum Erlangen - Medizinische Klinik 5, Erlangen

09000

RECRUITING

Ghent University Hospital, Ghent

03000

NOT_YET_RECRUITING

Universitair Ziekenhuis (Uz) Leuven, Leuven

02100

NOT_YET_RECRUITING

The Finsen Centre National Hospital, Copenhagen

00165

RECRUITING

Ospedale Pediatrico Bambino Gesu Irccs, Rome

03584

RECRUITING

Princess Maxima Center For Pediatric Oncology, Utrecht

08035

RECRUITING

Hospital General Universitario Vall D Hebron, Barcelona

RECRUITING

Hospital Sant Joan de Deu de Manresa, Barcelona

171 76

NOT_YET_RECRUITING

Karolinska Universitetssjukhuset Solna, Solna

B15 2TH

NOT_YET_RECRUITING

University Hospital Birmingham, Birmingham

G514TF

NOT_YET_RECRUITING

Royal Hospital For Sick Children Yorkhill Glasgow, Glasgow

L12 2AP

NOT_YET_RECRUITING

Alder Hey Childrens Nhs Foundation Trust, Liverpool

SM2 5PT

RECRUITING

The Royal Marsden Nhs Foundation Trust - Sutton, Sutton

SW3 6JJ

NOT_YET_RECRUITING

The Royal Marsden NHS Foundation Trust, Sutton