Sirolimus in Previously Treated Idiopathic Multicentric Castleman Disease

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

7

Participants

Timeline

Start Date

September 25, 2019

Primary Completion Date

June 30, 2024

Study Completion Date

June 30, 2026

Conditions
Castleman DiseaseCastleman's Disease, Multicentric
Interventions
DRUG

Sirolimus

Sirolimus (also known as rapamycin) inhibits the mTOR protein kinase and is approved by the USA FDA for the prevention of allograft rejection in renal transplant patients ≥ 13 years of age and for the treatment of lymphangioleiomyomatosis.

Trial Locations (4)

19104

Children's Hospital of Philadelphia, Philadelphia

University of Pennsylvania, Philadelphia

72205

University of Arkansas for Medical Sciences, Little Rock

92093

University of California - San Diego, La Jolla

All Listed Sponsors
lead

University of Pennsylvania

OTHER