29
Participants
Start Date
April 30, 2019
Primary Completion Date
April 30, 2021
Study Completion Date
October 31, 2025
Capecitabine
Capecitabine 825 mg/m2 orally twice-daily, 5 days a week for a total of 28 days, given with radiation therapy
Radiation therapy
1.8 Gy/day, 5 days a week for a total of 28 days, given with Capecitabine
mFOLFOX6
oxaliplatin 85 mg/m2, leucovorin 400 mg/m2 and fluorouracil 400 mg/m2 IV, fluorouracil 2400 mg/m2 IV (a 46 hrs CI), day 1 of each treatment cycle, every 2 weeks, given with nivolumab
Nivolumab
Nivolumab 240mg IV, day 1 of each treatment cycle, every two weeks, given with mFOLFOX6
RECRUITING
Rabin Medical Center, Beilinson Hospital, Petah Tikva
Collaborators (1)
Bristol-Myers Squibb
INDUSTRY
Baruch Brenner
OTHER