A Clinical Trial to Evaluate AZD7648 Alone and in Combination With Other Anti-cancer Agents in Patients With Advanced Cancers.

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

October 9, 2019

Primary Completion Date

December 7, 2022

Study Completion Date

December 7, 2022

Conditions
Advanced Malignancies
Interventions
DRUG

AZD7648

Core: AZD7648 will be administered orally

DRUG

PLD

The starting dose of PLD is 40 mg/m\^2, administered by intravenous infusion once every 4 weeks, for a maximum of 6 cycles

Trial Locations (5)

77030

Research Site, Houston

06510

Research Site, New Haven

EC1A 7BE

Research Site, London

SE1 9RT

Research Site, London

NE7 7DN

Research Site, Newcastle upon Tyne

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Parexel

INDUSTRY

lead

AstraZeneca

INDUSTRY