PD-1 Antibody Combined With Chemoradiotherapy in Recurrent Nasopharyngeal Carcinoma Patients

PHASE3RecruitingINTERVENTIONAL
Enrollment

212

Participants

Timeline

Start Date

March 1, 2020

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2028

Conditions
Recurrent Nasopharyngeal Carcinoma
Interventions
DRUG

PD-1 blocking antibody

Toripalimab 240mg, D1, every 3 weeks per cycle

DRUG

GP

Gemcitabine 1.0g/m2, D1 and D8; Cisplatin 80mg/m2, D1, every 3 weeks per cycle, total three cycles

RADIATION

IMRT

IMRT 60-66Gy, 1.8-2.0Gy/f/day

Trial Locations (12)

Unknown

RECRUITING

Sun Yat-sen University Cancer Center, Guangzhou

NOT_YET_RECRUITING

Peking University Third Hospital, Beijing

NOT_YET_RECRUITING

Sichuan Cancer Hospital, Chengdu

NOT_YET_RECRUITING

Fujian Province Cancer Hospital, Fuzhou

RECRUITING

Guizhou Cancer Hospital, Guiyang

NOT_YET_RECRUITING

Zhejiang Cancer Hospital, Hangzhou

NOT_YET_RECRUITING

Jiangxi Cancer Hospital, Nanchang

RECRUITING

The First Affiliated Hospital of Guangxi Medical University, Nanning

NOT_YET_RECRUITING

Fudan University Shanghai Cancer Center, Shanghai

RECRUITING

Zhongnan Hospital of Wuhan University, Wuhan

RECRUITING

Xijing Hospital, Xi'an

NOT_YET_RECRUITING

The First Affiliated Hospital of Xiamen University, Xiamen

All Listed Sponsors
lead

Sun Yat-sen University

OTHER