AScalate: Treat-to-target in Axial Spondyloarthritis

PHASE3CompletedINTERVENTIONAL
Enrollment

304

Participants

Timeline

Start Date

June 4, 2019

Primary Completion Date

February 4, 2022

Study Completion Date

September 22, 2022

Conditions
Axial Spondyloarthritis
Interventions
BIOLOGICAL

Secukinumab/Adalimumab-Biosimilar

Secukinumab 150 mg, s.c. Secukinumab 300 mg, s.c. Adalimumab biosimilar 40 mg, s.c.

OTHER

Standard-of-care

Treatment according to local practice standards by the rheumatologist following latest treatment recommendations with NSAIDs as the first-choice drug treatment and DMARDs for patients with active disease despite the use (or intolerance/contraindication) of NSAIDs.

Trial Locations (47)

12161

Novartis Investigative Site, Berlin

12163

Novartis Investigative Site, Berlin

13125

Novartis Investigative Site, Berlin

13353

Novartis Investigative Site, Berlin

14059

Novartis Investigative Site, Berlin

14469

Novartis Investigative Site, Potsdam

18209

Novartis Investigative Site, Bad Doberan

20095

Novartis Investigative Site, Hamburg

22391

Novartis Investigative Site, Hamburg

22415

Novartis Investigative Site, Hamburg

24768

Novartis Investigative Site, Rendsburg

31059

Novartis Investigative Site, Toulouse

31134

Novartis Investigative Site, Hildesheim

31812

Novartis Investigative Site, Bad Pyrmont

34295

Novartis Investigative Site, Montpellier

35630

Novartis Investigative Site, Ehringshausen

37170

Novartis Investigative Site, Chambray-lès-Tours

38043

Novartis Investigative Site, Grenoble

39104

Novartis Investigative Site, Magdeburg

39110

Novartis Investigative Site, Magdeburg

39245

Novartis Investigative Site, Gommern

40878

Novartis Investigative Site, Ratingen

44093

Novartis Investigative Site, Nantes

44649

Novartis Investigative Site, Herne

45100

Novartis Investigative Site, Orléans

50937

Novartis Investigative Site, Cologne

53105

Novartis Investigative Site, Bonn

54292

Novartis Investigative Site, Trier

54511

Novartis Investigative Site, Vandœuvre-lès-Nancy

55131

Novartis Investigative Site, Mainz

69300

Novartis Investigative Site, Caluire-et-Cuire

72000

Novartis Investigative Site, Le Mans

75013

Novartis Investigative Site, Paris

79106

Novartis Investigative Site, Freiburg im Breisgau

80639

Novartis Investigative Site, München

81377

Novartis Investigative Site, München

85925

Novartis Investigative Site, La Roche-sur-Yon

87000

Novartis Investigative Site, Limoges

89073

Novartis Investigative Site, Ulm

91056

Novartis Investigative Site, Erlangen

06001

Novartis Investigative Site, Nice

09130

Novartis Investigative Site, Chemnitz

03042

Novartis Investigative Site, Cottbus

01067

Novartis Investigative Site, Dresden

01307

Novartis Investigative Site, Dresden

09599

Novartis Investigative Site, Freiberg

07548

Novartis Investigative Site, Gera

Sponsors
All Listed Sponsors
lead

Novartis Pharmaceuticals

INDUSTRY