Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

66

Participants

Timeline

Start Date

July 25, 2019

Primary Completion Date

March 31, 2026

Study Completion Date

February 21, 2030

Conditions
Medulloblastoma, ChildhoodMedulloblastoma RecurrentMedulloblastoma
Interventions
DRUG

CX 4945

CX-4945 is supplied as 200 mg capsules delivered orally as a formulated API

Trial Locations (12)

10065

Memorial Sloan-Kettering Cancer Center, New York

15201

Children's Hospital of Pittsburgh of UPMC, Pittsburgh

20010

Children's National Medical Center, Washington D.C.

30322

Children's Healthcare of Atlanta, Atlanta

32608

University of Florida, Gainesville

38105

St. Jude Children Research Hospital, Memphis

43205

Nationwide Children's Hospital, Columbus

45229

Cincinnati Children's Hospital Medical Center, Cincinnati

60611

Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago

77030

Baylor College of Medicine, Houston

90026

Children's Hospital of Los Angeles, Los Angeles

94304

Stanford University and Lucile Packard Children's Hospital, Palo Alto

All Listed Sponsors
collaborator

Senhwa Biosciences, Inc.

INDUSTRY

collaborator

National Cancer Institute (NCI)

NIH

collaborator

St. Jude Children's Research Hospital

OTHER

lead

Pediatric Brain Tumor Consortium

NETWORK

NCT03904862 - Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery | Biotech Hunter | Biotech Hunter