Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV

NAActive, not recruitingINTERVENTIONAL
Enrollment

360

Participants

Timeline

Start Date

December 19, 2019

Primary Completion Date

December 1, 2024

Study Completion Date

February 28, 2025

Conditions
Human Immunodeficiency VirusSmoking CessationSmoking, CigaretteSmokingAnxietyDepressionNicotine Dependence
Interventions
BEHAVIORAL

QUIT

QUIT is a transdiagnostic Cognitive Behavioral Therapy-based smoking cessation protocol designed to address distress intolerance, anxiety sensitivity, and anhedonia in people living with HIV who smoke. QUIT is delivered in 9 60-minute individual weekly sessions over a 10-week period. Sessions are active, with treatment components practiced within and outside of the session. Participants will also receive the transdermal nicotine patch for 8 weeks, starting when they attempt to quit smoking during week 7 of the study.

BEHAVIORAL

Time-Matched Control (TM)

Participants will receive a standard smoking cessation treatment, based on the clinical practice guidelines from the U.S. Department of Health and Human Services, Treating Tobacco Use and Dependence. Treatment will be delivered in nine, 60-minute sessions over a ten-week period. The treatment is based on a treatment protocol developed and used previously by Dr. Zvolensky. Because clinical guidelines recommend that all smokers attempting to quit smoking receive pharmacotherapy, participants will also receive the transdermal nicotine patch for 8 weeks.

Trial Locations (3)

77009

Thomas Street Health Center, Houston

02114

Massachusetts General Hospital, Boston

02215

Fenway Community Health, Boston

All Listed Sponsors
collaborator

The Fenway Institute

OTHER

collaborator

University of Texas at Austin

OTHER

collaborator

University of Houston

OTHER

collaborator

Baylor College of Medicine

OTHER

collaborator

Southern Methodist University

OTHER

lead

Massachusetts General Hospital

OTHER