1,000
Participants
Start Date
November 1, 2016
Primary Completion Date
May 31, 2026
Study Completion Date
May 31, 2026
Tocilizumab
The scramble TA group is given bioagents such as IL-6R antibody, CD20-antibody, TNF-alpha antibody, and other bioagents which are safe to use in human to treat other refractory diseases. The sham group is given cyclophosphamide. And the prednisone is the basic drugs to be used in TA.
Leflunomide
The scramble TA group is given new molecules such as Leflunomide, Iguratimod, and other molecules which are safe to use in human to treat other refractory diseases. The sham group is also given cyclophosphamide. And the prednisone is the basic drugs to be used in TA.
RECRUITING
Department of Rheumatology in Zhongshan hospital, Fudan University, Shanghai
Shanghai Zhongshan Hospital
OTHER