Intralesional Cemiplimab for Adult Patients With Cutaneous Squamous Cell Carcinoma or Basal Cell Carcinoma

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

97

Participants

Timeline

Start Date

April 11, 2019

Primary Completion Date

November 22, 2025

Study Completion Date

February 2, 2026

Conditions
Cutaneous Squamous Cell CarcinomaBasal Cell Carcinoma
Interventions
DRUG

Cemiplimab

Each patient will receive intralesional injections of cemiplimab every week (QW), or at less frequent dosing into the lesion at the assigned dose level for 3-12 weeks prior to scheduled surgery

Trial Locations (18)

3000

Peter MacCallum Cancer Centre, Melbourne

3004

Alfred Health, Melbourne

4102

Princess Alexandra Hospital, Brisbane

6160

Fremantle Dermatology, Fremantle

14564

Rochester Dermatologic Surgery, P.C., Victor

22031

Inova Schar Cancer Institute, Fairfax

27710

Duke Cancer Center, Durham

30342

MetroDerm, Atlanta

33445

Dermatology Associates of the Palm Beaches, Delray Beach

77030

The University of Texas MD Anderson Cancer Center, Houston

85006

Medical Dermatology Specialists, Phoenix

92123

TCR Medical Corporation, San Diego

01915

Northeast Dermatology Associates, Beverly

6500 HB

Radboud University Medical Center, Nijmegen

6202 AZ

Maastricht University Medical Center, Maastricht

1066 CX

The Netherlands Cancer Institute - Antoni van Leeuwenhoek, Amsterdam

9700 RB

University of Groningen, University Medical Centre Groningen, Groningen

3015 GD

Erasmus MC, Rotterdam

All Listed Sponsors
lead

Regeneron Pharmaceuticals

INDUSTRY