Open-Label CA-008 (Vocacapsaicin) in Bunionectomy

Drug: CA-008 4.2 mg reconstituted in saline

30 mg IV at the onset of anesthesia

1 g at the onset of anesthesia

100 mcg IV fentanyl administered at the onset of anesthesia and additional 50 mcg near the end of surgery

0.25% 30 mL (75 mg) prior to surgery

1.5% 12 mL at the end of surgery

200 mg PO bid each day postoperative

1 g postoperative

2% 15 mL at the end of surgery

Bupivacaine liposome injection suspension