Assessing the Response Rate of Neo-adjuvant Taxotere and Trastuzumab in Nigerian Women With Breast Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

November 25, 2019

Primary Completion Date

September 10, 2023

Study Completion Date

April 10, 2024

Conditions
Breast CancerBreast Cancer FemaleHER2-positive Breast CancerBreast Cancer Stage IIBreast Cancer Stage III
Interventions
DRUG

Docetaxel

Administered to all patients for a minimum of 4 cycles for 12 weeks.

DRUG

Herceptin

Administered for 18 cycles every three weeks (52 weeks) for each patient starting at the first day of treatment with docetaxel.

DRUG

FEC

Only administered to patients who received docetaxel and herceptin and were assessed as having poor response (defined as stable disease or progressive disease or partial response inoperable).

DRUG

Tamoxifen

Only administered to hormone-receptor positive patients. Patients will receive tamoxifen or letrozole.

DRUG

Letrozole

Only administered to hormone-receptor positive patients. Patients will receive tamoxifen or letrozole.

DRUG

LHRH agonist

Administered to all premenopausal patients.

Trial Locations (1)

Unknown

RECRUITING

University College Hospital, Ibadan, Nigeria, Ibadan

All Listed Sponsors
lead

University of Chicago

OTHER

NCT03879577 - Assessing the Response Rate of Neo-adjuvant Taxotere and Trastuzumab in Nigerian Women With Breast Cancer | Biotech Hunter | Biotech Hunter