First-in-Human Study of EOS100850 (Inupadenant) in Patients with Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

119

Participants

Timeline

Start Date

February 5, 2019

Primary Completion Date

May 28, 2024

Study Completion Date

May 28, 2024

Conditions
Solid Tumor, Adult
Interventions
DRUG

EOS100850

Oral administration

DRUG

Pembrolizumab

IV Infusion

DRUG

Chemotherapy

Standard of Care IV Infusion

Trial Locations (19)

1070

Institut Jules Bordet, Anderlecht

1200

UCL Saint-Luc, Brussels

2610

Hospital GZA Sint-Augustinus, Wilrijk

9000

UZ Ghent, Ghent

20014

Onkologikoa, San Sebastián

28050

START Madrid-HM CIOCC Hospital Universitario HM Sanchinarro, Madrid

31008

Universidad de Navarra - Clinica Universitaria de Navarra, Pamplona

44805

Centre de Lutte Contre le Cancer - Institut de Cancerologie de l'Ouest - Rene Gauducheau, Saint-Herblain

48201

Karmanos Cancer Institute, Michigan Center

69008

Centre de Lutte Contre le Cancer (CLCC) - Universite de Lyon - Centre Leon-Berard, Lyon

86021

Centre Hospitalier Universitaire de Poitiers - Hopital la Miletrie- Pôle Régional de Cancérologie, Poitiers

94805

Gustave Roussy, Villejuif

07601

John Theurer Cancer Center, Hackensack University Medical Center, Hackensack

78229-3900

University of Texas Health Science Center at San Antonio, San Antonio

03722

Yonsei University Severance Hospital, Seoul

06351

Samsung Medical Center, Seoul

06591

St Mary's Hospital, The Catholic University of Korea, Seoul

08003

Hospital del Mar, Barcelona

SM2 5PT

The Royal Marsden NHS Foundation Trust - Royal Marsden Hospital, Sutton

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

iTeos Belgium SA

INDUSTRY

collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

iTeos Therapeutics

INDUSTRY

NCT03873883 - First-in-Human Study of EOS100850 (Inupadenant) in Patients with Cancer | Biotech Hunter | Biotech Hunter