64
Participants
Start Date
November 12, 2018
Primary Completion Date
December 30, 2025
Study Completion Date
December 31, 2025
Immediate weight loss
Upper body obese subjects will undergo behavioral intervention with a life coach and a physical activity program of their choice for 4 months.
Pioglitazone
Upper body obese subjects will be block randomized to pioglitazone or placebo at enrollment.
Deferred weight loss
Upper body obese subjects will complete a weight-stable period of 4 months and subsequently undergo behavioral intervention with a life coach and a physical activity program of their choice for 4 months.
Placebo
Upper body obese subjects will be block randomized to pioglitazone or placebo at enrollment.
RECRUITING
Mayo Clinic in Rochester, Rochester
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Mayo Clinic
OTHER