Changes in fMRI and Neurocognitive Function in Women With Pre-eclampsia

TerminatedOBSERVATIONAL
Enrollment

18

Participants

Timeline

Start Date

July 7, 2014

Primary Completion Date

April 13, 2022

Study Completion Date

April 13, 2022

Conditions
Pre-EclampsiaNeurocognitive Dysfunction
Interventions
DIAGNOSTIC_TEST

Neuroimaging Procedures

"Subjects will complete neuroimaging procedures at 2-6-week postpartum or during hospitalization after delivery prior to discharge, which will consist of high-resolution anatomic, perfusion and resting-brain fMRI sequences; all of which will be acquired on a 3-Tesla General Electric magnetic resonance scanner~provided by the Brain Imaging and Analysis Center (BIAC) at Duke University. No contrast agent will be administered in these imaging procedures."

DIAGNOSTIC_TEST

Neuropsychological Assessment Procedures

Once identified as meeting study criteria and consented for participation, parturients will be tested during hospitalization or as outpatients for controls, and at 2-6 weeks postpartum with the following cognitive battery. Wechsler Test of Adult Reading (WTAR), CANTABeclipse Computerized Cognitive Assessment Measures, Stroop Color-Word Test, Controlled Oral Word Association Test, EuroQol, Beck Depression Inventory Revised

Trial Locations (1)

27710

Duke University Medical Center, Durham

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Duke University

OTHER

NCT03863639 - Changes in fMRI and Neurocognitive Function in Women With Pre-eclampsia | Biotech Hunter | Biotech Hunter