Decreased T1 Times and Impaired Myocardial Contractility in Anabolic Androgenic Steroids Users

CompletedOBSERVATIONAL
Enrollment

50

Participants

Timeline

Start Date

April 1, 2015

Primary Completion Date

April 1, 2016

Study Completion Date

April 1, 2017

Conditions
Focal Fibrosis
Interventions
DIAGNOSTIC_TEST

Cardiovascular Magnetic Resonance

The patients underwent to CMR examination on a Philips Achieve 1.5 device. Images were acquired coupled to the electrocardiogram and during respiratory pause, in four chambers, short axis and long axis of the left ventricle, in the same exact location in different sequences. A gradient - echo sequence (steady-state free precession) was used to evaluate cardiac function (functional evaluation). We will also evaluate T1 weighted images (T1 -relaxation times) and T2, performed sequentially, through spin-echo pulse (black-blood), triple inversion recovery sequence, for the morphological evaluation

DIAGNOSTIC_TEST

Transthoracic echocardiography

The images were collected by the Vivid E9. The patients were submitted to one-dimensional (M-mode), two-dimensional (B-mode), and three-dimensional (three-dimensional) echocardiographic studies. The images obtained were associated with pulsed, continuous and color Doppler.

Trial Locations (1)

05403-900

Instituto do Coração do Hospital da Clínicas da Universidade de Sao Paulo, São Paulo

All Listed Sponsors
collaborator

Fundação de Amparo à Pesquisa do Estado de São Paulo

OTHER_GOV

lead

University of Sao Paulo General Hospital

OTHER

NCT03862235 - Decreased T1 Times and Impaired Myocardial Contractility in Anabolic Androgenic Steroids Users | Biotech Hunter | Biotech Hunter