Trial of Rifaximin in Probable Alzheimer's Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

April 9, 2019

Primary Completion Date

November 19, 2020

Study Completion Date

November 19, 2020

Conditions
Alzheimer's Disease
Interventions
DRUG

Rifaximin 550 milligrams (MG)

Rifaximin (Xifaxan, Salix Pharmaceuticals, Bridgewater, N.J.) (See Package Insert) is a drug that is approved by the FDA for use in humans for the treatment of Hepatic Encephalopathy, Traveler's Diarrhea and Irritable Bowel Syndrome. It is commercially available. It will be used in accordance with approved labeling as pertains to dosage and administration for Hepatic Encephalopathy, contraindications and warnings. However, it will be used investigationally in this trial as rifaximin is not FDA approved for the treatment of Alzheimer's Disease.

Trial Locations (1)

27710

Duke University Medical Center, Durham

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Bausch Health Americas, Inc.

INDUSTRY

lead

Duke University

OTHER

NCT03856359 - Trial of Rifaximin in Probable Alzheimer's Disease | Biotech Hunter | Biotech Hunter