Research Study Investigating How Well NNC0174-0833 Works in People Suffering From Overweight or Obesity.

PHASE2CompletedINTERVENTIONAL
Enrollment

706

Participants

Timeline

Start Date

March 1, 2019

Primary Completion Date

March 2, 2020

Study Completion Date

March 25, 2021

Conditions
OverweightObesity
Interventions
DRUG

NNC0174-0833

Participants will get one dose of NNC0174-0833 once weekly. The medicine is injected with a thin needle in a skin fold in the stomach, thigh or upper arm using NovoPen® 4. Participants will gradually increase the dose until they reach the target dose, and will continue on the this dose once weekly up to 26 weeks.

DRUG

Placebo (NNC0174-0833)

Participants will get one dose of Placebo (NNC0174-0833) once weekly. The medicine is injected with a thin needle in a skin fold in the stomach, thigh or upper arm using NovoPen® 4. Participants will gradually increase the dose until they reach the target dose, and will continue on the this dose once weekly up to 26 weeks.

DRUG

Liraglutide 3.0 mg

Participants will get one dose of liraglutide 3.0 mg once daily. The medicine is injected with a thin needle in a skin fold in the stomach, thigh or upper arm using pre-filled PDS290 pen-injector. Participants will gradually increase their dose every week until they reach the target dose of 3.0 mg daily. The participants will continue on 3.0 mg of liraglutide, once daily up to 26 weeks.

DRUG

Placebo (Liraglutide 3.0 mg)

Participants will get one dose of Placebo (liraglutide 3.0 mg) once daily. The medicine is injected with a thin needle in a skin fold in the stomach, thigh or upper arm using pre-filled PDS290 pen-injector. Participants will gradually increase their dose every week until they reach the target dose of 3.0 mg. The participants will continue on Placebo (liraglutide 3.0 mg), once daily up to 26 weeks.

Trial Locations (54)

1466

Dr Wilhase's rooms, Boksburg

1812

Dr R Dulabh, Johannesburg

2650

Hvidovre Hospital Endokrinologisk forsknings afsnit 159, Hvidovre

4091

Dr Vawda's site, Durban

4450

Dr J Reddy, Durban

8200

Aarhus Universitetshospital Diabetes og Hormonsygdomme, Aarhus N

9300

FARMOVS (Pty) LTD, Bloemfontein

11000

Endocrinology, Diabetes and Metabolism Diseases Clinic, Belgrade

14609

Rochester Clinical Research, Inc., Rochester

20520

Turku University Hospital, Turku

21000

Clin. Centre Vojvodina, Clin. endocr., diab. and met. dis., Novi Sad

22206

Washington Center For Weight Management And Research,Inc., Arlington

23294

National Clinical Research Inc., Richmond

27408

PharmQuest, Greensboro

29303

Spartanburg Medical Research, Spartanburg

29341

Spectrum Medical Research, LLC, Gaffney

29425

Medical University of South Carolina, Charleston

32081

St Johns Center For Clinical Research, Ponte Vedra

32216

Jacksonville Center For Clinical Research, Jacksonville

33027

South Broward Research LLC, Pembroke Pines

34429

Nature Coast Clinical Research, Crystal River

40620

StudyCor, Jyväskylä

44281

Family Practice Center of Wadsworth, Inc., Wadsworth

45005

Prestige Clinical Research, Franklin

60607

Cedar-Crosse Research Center, Chicago

70211

Itä-Suomen yliopisto, Kuopio

73069

Lynn Institute of Norman, Norman

78681

Texas Diabetes & Endocinology, Round Rock

91978

Encompass Clinical Research, Spring Valley

92801

Anaheim Clinical Trials, LLC, Anaheim

21075-6437

Centennial Medical Group, Elkridge

02747

Infinity Medical Research, North Dartmouth

45040-6815

Albert J Weisbrot, Mason

37620-7352

Holston Medical Group Pc, Bristol

T2T 5C7

University of Calgary, Calgary

T2V 4J2

C-endo Diabetes & Endocrinology Clinic, Calgary

T6H 2L4

C-endo Diabetes & Endocrinology Clinic, Edmonton

L8L 5G8

The Wharton Medical Clinic Clinical Trials, Hamilton

L8M 1K7

Hamilton Medical Research Group, Hamilton

00014

Obesity Research Unit, University of Helsinki

DUBLIN 4

Clinical Research Centre, St. Vincent's University Hospital,, Dublin

103-0027

Tokyo-Eki Center-building Clinic, Tokyo

103-0028

Tokyo Center Clinic, Tokyo

160-0008

ToCROM Clinic, Tokyo

15-281

Gabinet Leczenia Otylosci i Chorob Dietozaleznych, Bialystok

40-001

Centrum Medyczne Salvia, Katowice

60-589

Centrum Zdrowia Metabolicznego, Poznan

BA15 1DQ

The Health Centre, Bradford-on-Avon

BS10 5NB

Southmead Hospital, Bristol

CV2 2DX

WISDEM Centre, Coventry

L9 7AL

University Hospital Aintree, Liverpool

SE1 9RT

Guys Hospital, London

WC1E 6JF

UCL - Obesity, London

S65 1DA

Clifton Medical Centre, Rotherham

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Novo Nordisk A/S

INDUSTRY