NCT03849443View on ClinicalTrials.gov

Single Versus Multi-Dose Oral and Intravenous Tranexamic Acid Patients at High Risk for Blood Transfusion After Spine Surgery

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

604

Participants

Timeline

Start Date

August 26, 2019

Primary Completion Date

December 1, 2025

Study Completion Date

January 1, 2026

Conditions
Open Posterior Thoracolumbar Spinal Fusion Procedure
Interventions
DRUG

Tranexamic Acid Injectable Product (1000 mg intravenous bolus)

Intravenous methods to decrease blood loss

DRUG

Vitamin C 250 MG Oral Tablet

Oral method of placebo

DRUG

Tranexamic Acid 650Mg Tablet

Oral method of treatment group

Trial Locations (1)

6060712

RECRUITING

Rush University Medical Center, Chicago

All Listed Sponsors
lead

Rush University Medical Center

OTHER