Rickettsiae in Myanmar

CompletedOBSERVATIONAL
Enrollment

700

Participants

Timeline

Start Date

June 20, 2019

Primary Completion Date

October 25, 2019

Study Completion Date

October 25, 2019

Conditions
Rickettsiae Infections
Interventions
DIAGNOSTIC_TEST

MORU in-house ELISA test followed by IFA if positive

An in-house rickettsial IgG ELISA test will be used for this study to determine previous rickettsial infections by measuring IgG levels. All specimens will be tested for IgG antibodies using ELISA tests for scrub typhus (Orientia tsutsugamushi strains Karp, Kato, Gilliam and TA716), murine typhus (Rickettsia typhi strain type Wilmington), and spotted fever rickettsiosis (Rickettsia honei and Rickettsia conorii). If the sample tests positive, it will be retested for the same antigens using the IFA test. The sample will be considered positive if both the ELISA and the IFA are positive.

Trial Locations (1)

Unknown

Myanmar Oxford Clinical Research Unit, Yangon

All Listed Sponsors
collaborator

National Health Laboratory, Myanmar

UNKNOWN

collaborator

Magway General Hospital, Magway

UNKNOWN

collaborator

Monywa Hospital, Sagaing

UNKNOWN

collaborator

Mandalay General Hospital and University of Medicine, Mandalay

UNKNOWN

collaborator

University of Medicine, Magway

UNKNOWN

collaborator

Mahidol Oxford Tropical Medicine Research Unit

OTHER

collaborator

Medical Action Myanmar

OTHER

lead

Myanmar Oxford Clinical Research Unit

OTHER