56
Participants
Start Date
December 17, 2018
Primary Completion Date
June 25, 2024
Study Completion Date
June 25, 2024
GT005
GT005 is a recombinant, non-replicating AAV2 expressing human complement factor I (CFI). GT005 was administered as a single time subretinal injection into the study eye of subjects allocated to one of the two GT005 doses.
GT005 / Device: Orbit™ Subretinal Delivery System
"GT005 is a recombinant, non-replicating AAV2 expressing human complement factor I (CFI).~A single dose of GT005 was administered with subretinal injection via suprachoroidal cannulation approach.~Device: Orbit™ Subretinal Delivery System"
Mid-Atlantic Retina, Philadelphia
Cincinnati Eye Institute, Cincinnati
Midwest Eye Institute, Indianapolis
Wolfe Eye Clinic, West Des Moines
Pepose Vision Institute, Chesterfield
Sierra Eye Associates, Reno
Ophthalamic Consultants of Boston (OCB), Boston
Bristol Eye Hospital, Bristol
Moorfields Eye Hospital, London
Manchester Eye Hospital, Manchester
Oxford University Hospital, Oxford
Sunderland Eye Infirmary, Sunderland
Retina Clinic London, London
Lead Sponsor
Collaborators (1)
Novartis Pharmaceuticals
INDUSTRY
Gyroscope Therapeutics Limited
INDUSTRY