Trial Comparing a Multi-Modal Pain Protocol With and Without Opioids Following Total Joint Arthroplasty

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

April 10, 2019

Primary Completion Date

July 28, 2020

Study Completion Date

July 28, 2020

Conditions
Total Knee Arthroplasty
Interventions
DRUG

Oxycodone

The primary endpoint will be pain scores, calculated by the Visual Analog Scale. This score will be collected daily during the hospital examination and by phone surveys for two weeks following discharge. Investigators hypothesize that the non-opioid pain regimen will provide equivalent relief as compared to the opioid regimen.

DRUG

Placebo Oral Tablet

The primary endpoint will be pain scores, calculated by the Visual Analog Scale. This score will be collected daily during the hospital examination and by phone surveys for two weeks following discharge. Investigators hypothesize that the non-opioid pain regimen will provide equivalent relief as compared to the opioid regimen.

Trial Locations (1)

32224

Mayo Clinic in Florida, Jacksonville

All Listed Sponsors
collaborator

Ambit Biosciences Corporation

INDUSTRY

collaborator

Kern Medical Center

OTHER

lead

Mayo Clinic

OTHER

NCT03845881 - Trial Comparing a Multi-Modal Pain Protocol With and Without Opioids Following Total Joint Arthroplasty | Biotech Hunter | Biotech Hunter