Brain Markers Predicting Reading Recovery After Stroke

CompletedOBSERVATIONAL
Enrollment

26

Participants

Timeline

Start Date

April 4, 2018

Primary Completion Date

July 1, 2021

Study Completion Date

July 1, 2021

Conditions
Left-Hemisphere Stroke
Interventions
DIAGNOSTIC_TEST

Perfusion functional Magnetic Resonance Imaging (perfusion fMRI)

The goal of this test is to measure brain activity during subacute and chronic post-stroke period using a widely available non-invasive neuroimaging tool - functional Magnetic Resonance Imaging (fMRI). Because fMRI relies in part on cerebral blood flow, which is altered in stroke, measuring longitudinal changes in neural activity with fMRI requires that we control for concomitant changes in blood circulation. To do this, we will employ a novel dual-echo perfusion fMRI sequence, which will allow us to separately estimate neural and vascular contributions to fMRI.

Trial Locations (1)

07052

Kessler Foundation, West Orange

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Rutgers University

OTHER

collaborator

National Center for Medical Rehabilitation Research (NCMRR)

NIH

lead

Kessler Foundation

OTHER