NCT03845166 - A Study of XL092 as Single-Agent and Combination Therapy in Subjects With Solid Tumors | Biotech Hunter

Enrollment

325

Participants

Timeline

Start Date

March 20, 2019

Primary Completion Date

August 31, 2026

Study Completion Date

May 31, 2027

Conditions

Neoplasm MalignantRenal Cell CarcinomaHormone Receptor Positive Breast CarcinomaMetastatic Castration-resistant Prostate CancerColorectal Cancer

Interventions

DRUG

XL092

oral doses of XL092

DRUG

Atezolizumab

Supplied as 1200 mg/20 mL vials; administered as a 1200 mg IV infusion once every 3 weeks (q3w)

DRUG

Avelumab

Supplied as 200 mg/10 mL vials; administered as an 800 mg IV infusion once every 2 weeks (q2w)

Trial Locations (86)

1200

Exelixis Clinical Site #51, Brussels

2010

Exelixis Clinical Site #52, Darlinghurst

2170

Exelixis Clinical Site #53, Liverpool

2650

Exelixis Clinical Site #44, Edegem

3084

Exelixis Clinical Site #63, Heidelberg

4101

Exelixis Clinical #75, South Brisbane

5037

Exelixis Clinical Site #56, Kurralta Park

9000

Exelixis Clinical Site #65, Ghent

10021

Exelixis Clinical Site #86, New York

10029

Exelixis Clinical Site #35, New York

10065

Exelixis Clinical #78, New York

10461

Exelixis Clinical Site #85, The Bronx

13009

Exelixis Clinical Site #48, Marseille

14076

Exelixis Clinical Site #32, Caen

15232

Exelixis Clinical Site #12, Pittsburgh

15706

Exelixis Clinical Site #20, Santiago de Compostela

17033

Exelixis Clinical Site #59, Hershey

19107

Exelixis Clinical Site #58, Philadelphia

20132

Exelixis Clinical Site #67, Milan

20141

Exelixis Clinical Site #54, Milan

20249

Exelixis Clinical Site #64, Hamburg

21201

Exelixis Clinical Site #44, Baltimore

22903

Exelixis Clinical Site #8, Charlottesville

23219

Exelixis Clinical Site #43, Richmond

27100

Exelixis Clinical Site #69, Pavia

28007

Exelixis Clinical Site #81, Madrid

28040

Exelixis Clinical Site #34, Madrid

28041

Exelixis Clinical Site #55, Madrid

28046

Exelixis Clinical Site #17, Madrid

29425

Exelixis Clinical Site #61, Charleston

29572

Exelixis Clinical Site #50, Myrtle Beach

30322

Exelixis Clinical Site #11, Atlanta

30342

Exelixis Clinical Site #80, Atlanta

31059

Exelixis Clinical Site #57, Toulouse

32746

Exelixis Clinical Site #15, Lake Mary

33000

Exelixis Clinical #72, Bordeaux

33136

Exelixis Clinical Site #24, Miami

37203

Exelixis Clinical Site #87, Nashville

38138

Exelixis Clinical Site #33, Germantown

41013

Exelixis Clinical Site #16, Seville

44106

Exelixis Clinical Site #60, Cleveland

44805

Exelixis Clinical Site #37, Saint-Herblain

45219

Exelixis Clinical #74, Cincinnati

48109

Exelixis Clinical Site #45, Ann Arbor

48149

Exelixis Clinical Site #31, Münster

49546

Exelixis Clinical Site #2, Grand Rapids

52242

Exelixis Clinical Site #41, Iowa City

55101

Exelixis Clinical Site #25, Saint Paul

63011

Exelixis Clinical Site #46, Clermont

66205

Exelixis Clinical Site #36, Westwood

68130

Exelixis Clinical Site #13, Omaha

69495

Exelixis Clinical Site #39, Pierre-Bénite

72622

Exelixis Clinical Site #38, Nürtingen

75015

Exelixis Clinical Site #14, Paris

77030

Exelixis Clinical Site #3, Houston

78229

Exelixis Clinical Site #1, San Antonio

80131

Exelixis Clinical #73, Napoli

84112

Exelixis Clinical Site #5, Salt Lake City

86021

Exelixis Clinical Site #47, Poitiers

90025

Exelixis Clinical Site #7, Los Angeles

90095

Exelixis Clinical Site #84, Los Angeles

91010

Exelixis Clinical Site #6, Duarte

92093

Exelixis Clinical Site #49, La Jolla

92150

Exelixis Clinical Site #22, Suresnes

94158

Exelixis Clinical Site #66, San Francisco

94305

Exelixis Clinical Site #71, Stanford

94805

Exelixis Clinical #77, Villejuif

99208

Exelixis Clinical Site #26, Spokane

04074

Exelixis Clinical Site #62, Scarborough

02215

Exelixis Clinical Site #4, Boston

08816

Exelixis Clinical Site #9, East Brunswick

08903

Exelixis Clinical Site #83, New Brunswick

656 91

Exelixis Clinical Site #21, Brno

500 05

Exelixis Clinical Site #42, Hradec Králové

779 00

Exelixis Clinical Site #10, Olomouc

140 59

Exelixis Clinical Site #27, Prague

1066 CX

Exelixis Clinical Site #79, Amsterdam

3015 GD

Exelixis Clinical #76, Rotterdam

08208

Exelixis Clinical Site #23, Sabadell

08003

Exelixis Clinical Site #18, Barcelona

08023

Exelixis Clinical Site #19, Barcelona

08035

Exelixis Clinical Site #29, Barcelona

08036

Exelixis Clinical Site #30, Barcelona

W1G6AD

Exelixis Clinical #70, London

SM2 5PT

Exelixis Clinical Site #40, Sutton

PR29HT

Exelixis Clinical Site #68, Preston